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Friday, July 10, 2015

Case of the Week -- TTP

Please see previous post on Thrombotic Thrombocytopenic Purpura (TTP):
http://internalvalidity.blogspot.ca/2008/10/day-110-ttp.html

The ORIGINAL CASE REPORT by MOSCHCOWITZ in 1925 Archives of Internal medicine!
http://archinte.jamanetwork.com.proxy3.library.mcgill.ca/article.aspx?articleid=534853

2006 NEJM Review of the topic:
http://www.nejm.org/doi/full/10.1056/NEJMcp053024

Classic FFP in TTP paper (FFP is better than nothing):
http://www.nejm.org.proxy3.library.mcgill.ca/doi/full/10.1056/NEJM197712222972507

The Classic PLEX is better than FFP paper:
http://www.nejm.org/doi/full/10.1056/NEJM199108083250604

Drug-induced TTP:
http://www.ncbi.nlm.nih.gov/pubmed/25414441

HIV presenting as TTP (I've seen two!):
http://www.ncbi.nlm.nih.gov/pubmed/7926980

Risk of relapse in TTP:
http://www.ncbi.nlm.nih.gov/pubmed/7887549

Bonus -- approach to hemolytic anemia from my CMR teaching deck
http://chiefmedicalresident.blogspot.ca/2008/08/day-39-anemia.html





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